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| September 2000 Vol. 40 SUPPLEMENT 1 | ||||||
| BIOPHYSICS The Biophysical Society of Japan The 38th Annual Meeting Speech Draft Documentation Sept. 10, 2000 (Sun.) ・Sept. 13, 2000 (Wed.) Kawachi Kita Campus of Tohoku University Home page Info. The Biophysical Society of Japan: http://biophys.bio.niigata-u.ac.jp/ The 38th Annual Seminar: http://bp2000.phys.tohoku.ac.jp Sponsored by the Biophysical Society of Japan BIOPHYSICS THE BIOPHYSICS SOCIETY OF JAPAN 2E1700 |
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| The effect by Blended Herb against anti-tumor effect of mice with cancer | ||||||
| By M1iyabi Tanaka
, KIPPO INC. It is considered important that we endeavor to prevent our body oxidized in our daily life. So have we focused that blended herb has a reducing power. In this research, we used sample mice with cancer and measured changes in ecosystem of cytekinin and tumor volume by applying blended herb. The sample of the study was mice with Colon26 cancer, and we started applying blended herb to the mice from the next day after we had prepared them. Blended herb was applied after it had resolved in distilled water. The amount of 200mg/kg was applied for 14 days successively using a per os method. For the comparative group, we applied distilled water. On the last day of the study, we measured each model's tumor volume, and cytekinin IL-12 and TNF-α. The average tumor volume for the comparative group was 626.38 mm3 while the blended herb model was 330.02 mm3, though there was difference in mice size. We found the preventive effect against mice's tumor growth in terms of volume for blended herb samples. For the cytekinin, we did not see any difference for IL-12. On the contrary, for TNF-α, we saw a high generation of 20.45pg/ml for the comparative group and 37.46pg/ml for the herb group. Considering these results, we assumed blended herb prevents tumor growth of the sample mice with Colon26 cancer by its booster effect of TNF-α generation. |
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| The 3rd Annual Meeting of the Japanese Society for Complementary & Alternative Medicine & Treatment | ||||||
| December. 4, 2000 (Sat.) ・December.
5, 2000 (Sun.) KEIO-PLAZA HOTEL KIPPO's effect on side effects caused by radiotherapy and chemotherapy By Miyabi Tanaka, KIPPO Inc. [Objectives] KIPPO is functional food that enhances the resistance of human body against oxidization and is made by blending more than 10 different kinds of natural herbs. By conducting a test study of mice with cancer for 14 days, KIPPO has been proved to reduce the tumor volume to 52.7% compared with the result brought by chemotherapy by enhancing the TNF-α producing ability. It is said that a patient produces active oxygen inside his or her own body when he/she feels uneasy or gets stress from radiotherapy, chemotherapy or even facing the disease. At this time, we conducted two different test studies to verify the linkage between KIPPO and active oxygen. Test 1. We assumed active oxygen generated by aerobic exercise as the side effect of radiotherapy and chemotherapy and measured a change in the concentration of hyper lipid in blood when a sample mouse was forced to have aerobic exercise. Test 2. We measured the concentration of hyper lipid in blood when we gave a stress to a sample mouse. [Methods] (For both Tests 1 and 2) After solved KIPPO in distilled water, we gave each of sample mice an amount of 200mg/kg with per os dose for three days. For sample mice in the comparative group, we gave only water. As the aerobic exercise for Test 1, We set the speed of treadmill at 23m/m, and had them the exercise for 20 minutes. As the stress load of Test 2, we exposed an air jet of 3,000w to sample mice for 20 minutes. (For both Tests 1 and 2) After the test raise period, we extracted blood from the main artery of abdomen of each mouse and measured the concentrations of hyper lipid in blood at two different times; just after the exercise or stress load and after 30 minutes of them by using the TBA-fluorescent technique as the measurement records of plasma. [Result] We compared the results of both sample mice groups for Tests 1 and 2. The concentration of hyper lipid in blood of mice in the KIPPO group decreased at the both cases, just after the exercise and after 30 minutes of it. For the result taken after 30 minutes of the exercise, the concentration temporarily increased, but the other group lower compared it. Compared with the comparative group, the concentrations were reduced 60.6% and 50.0% for Test 1 and 50.0% and 46.1%, for just after the exercise or test load and after 30 minutes, respectively. [Conclusion] We confirmed that KIPPO has the certain ability to eliminate active oxygen. KIPPO also suggests that it reduce the side effects and stresses caused by radiotherapy and chemotherapy if it is taken before a patient starts those therapies. |
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| Test 1. Concentration
of plasma TBARS of exercise stress-rats in control and KIPPO-treated group
Test 2. Concentration of plasma TBARS of air jet stress-rats in control and KIPPO-treated group |
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